Administration during labour might depress respiration inside the neonate and an antidote for the kid really should be conveniently available.

Việc sử dụng đồng thời opioid với thuốc an thần như benzodiazepin hoặc các loại thuốc tương tự tăng nguy cơ an thần, ức chế hô hấp, hôn mê và tử vong do tác dụng ức chế thần kinh trung ương gia tăng.

Nên hạn chế liều lượng và thời gian sử dụng đồng thời của hai loại thuốc này.

The analgesic impact isn't materially Increased by raising the dose above that advised underneath; in severe scenarios the interval between doses ought to be reduced to get the requisite analgesic cover.

Swallow the tablets with a drink of h2o. Dihydrocodeine should if possible to taken just after foods, as This may help protect against feelings of sickness which can in some cases occur with the very first couple doses.

Generally take this medicine exactly as your medical doctor or pharmacist has advised you. Examine with your doctor or pharmacist if You aren't guaranteed.

Dihydrocodeine needs to be supplied in minimized doses or with caution to patients with asthma and lessened respiratory reserve. Keep away from use during an acute asthma assault.

four.5 Interaction with other medicinal products and other forms of interaction The concomitant usage of opioids with sedative medicines for instance benzodiazepines or associated drugs improves the threat of sedation, respiratory depression, coma and Demise on account of additive CNS depressant impact.

MAOIs taken with pethidine have been connected with serious CNS excitation or depression. Although this has not been documented with dihydrocodeine, it is possible that an identical interaction might happen with other opioid analgesics.

It's not a whole list of probable side effects. For those who see other effects not listed earlier mentioned, website Make contact with your health practitioner or pharmacist.

Gastric contents may well therefore have to be emptied, as this can be useful in eradicating unabsorbed drug, notably when a prolonged launch formulation has been taken.

Dihydrocodeine tablets should be swallowed complete, rather than damaged, chewed or crushed. The administration of damaged, chewed or crushed tablets may possibly result in a speedy release and absorption of a most likely fatal dose of dihydrocodeine and could cause overdose effects (see section four.9).

For those who have been having it for some time and wish to prevent it, your health practitioner will advocate that you just lower your dose slowly but surely in order to avoid the risk of these effects.

Drug withdrawal syndrome may perhaps occur on abrupt cessation of therapy or dose reduction. When a patient no longer calls for therapy, it truly is a good idea to taper the dose progressively to minimise symptoms of withdrawal. Tapering from a high dose could take months to months.